Design, synthesis and antiproliferative screening of newly synthesized acrylate derivatives as potential anticancer agents

A new series of acrylic acid and acrylate ester derivatives as modified analogs of tubulin polymerization inhibitors were designed and synthesized. The antiproliferative activity of the constructed molecules was investigated against MCF-7 breast carcinoma cells using CA-4 as positive molecule. Methy...

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Detalles Bibliográficos
Autores principales: Alshaya, Dalal Sulaiman, Tawakul, Rana M. O., Zaki, Islam, Abu Almaaty, Ali H., Fayad, Eman, Abd El-Aziz, Yasmin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402871/
https://www.ncbi.nlm.nih.gov/pubmed/37546218
http://dx.doi.org/10.1039/d3ra03849a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402871/
https://www.ncbi.nlm.nih.gov/pubmed/37546218
http://dx.doi.org/10.1039/d3ra03849a

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