Trimetazidine Affects Mitochondrial Calcium Uniporter Expression to Restore Ischemic Heart Function via Reactive Oxygen Species/NFκB Pathway Inhibition

Studies have demonstrated the roles of trimetazidine beyond being an antianginal agent in ischemic heart disease (IHD) treatment associated with mechanisms of calcium regulation. Our recent studies revealed that mitochondrial calcium uniporter (MCU, the pore-forming unit responsible for mitochondria...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiao, Zilong, Guan, Lichun, Shi, Hui, Yu, Yong, Yu, Ziqing, Qin, Shengmei, Su, Yangang, Chen, Ruizhen, Li, Minghui, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Cardiovascular Pharmacology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402877/
https://www.ncbi.nlm.nih.gov/pubmed/37163369
http://dx.doi.org/10.1097/FJC.0000000000001434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402877/
https://www.ncbi.nlm.nih.gov/pubmed/37163369
http://dx.doi.org/10.1097/FJC.0000000000001434

Ejemplares similares