Antibody-based soluble and membrane-bound TWEAK mimicking agonists with FcγR-independent activity

Fibroblast growth factor (FGF)-inducible 14 (Fn14) activates the classical and alternative NFκB (nuclear factor ‘kappa-light-chain-enhancer’ of activated B-cells) signaling pathway but also enhances tumor necrosis factor (TNF)-induced cell death. Fn14 expression is upregulated in non-hematopoietic c...

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Detalles Bibliográficos
Autores principales: Zaitseva, Olena, Hoffmann, Annett, Löst, Margaretha, Anany, Mohamed A., Zhang, Tengyu, Kucka, Kirstin, Wiegering, Armin, Otto, Christoph, Wajant, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402896/
https://www.ncbi.nlm.nih.gov/pubmed/37545514
http://dx.doi.org/10.3389/fimmu.2023.1194610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402896/
https://www.ncbi.nlm.nih.gov/pubmed/37545514
http://dx.doi.org/10.3389/fimmu.2023.1194610

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