PHRF1 promotes the class switch recombination of IgA in CH12F3-2A cells

PHRF1 is an E3 ligase that promotes TGF-β signaling by ubiquitinating a homeodomain repressor TG-interacting factor (TGIF). The suppression of PHRF1 activity by PML-RARα facilitates the progression of acute promyelocytic leukemia (APL). PHRF1 also contributes to non-homologous end-joining in respons...

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Detalles Bibliográficos
Autores principales: Lee, Jin-Yu, Chou, Nai-Lin, Yu, Ya-Ru, Shih, Hsin-An, Lin, Hung-Wei, Lee, Chine-Kuo, Chang, Mau-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403053/
https://www.ncbi.nlm.nih.gov/pubmed/37540725
http://dx.doi.org/10.1371/journal.pone.0285159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403053/
https://www.ncbi.nlm.nih.gov/pubmed/37540725
http://dx.doi.org/10.1371/journal.pone.0285159

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