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High-throughput screening identifies cell cycle-associated signaling cascades that regulate a multienzyme glucosome assembly in human cells

We have previously demonstrated that human liver-type phosphofructokinase 1 (PFK1) recruits other rate-determining enzymes in glucose metabolism to organize multienzyme metabolic assemblies, termed glucosomes, in human cells. However, it has remained largely elusive how glucosomes are reversibly ass...

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Detalles Bibliográficos
Autores principales: Schmitt, Danielle L., Dranchak, Patricia, Parajuli, Prakash, Blivis, Dvir, Voss, Ty, Kohnhorst, Casey L., Kyoung, Minjoung, Inglese, James, An, Songon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403072/
https://www.ncbi.nlm.nih.gov/pubmed/37540718
http://dx.doi.org/10.1371/journal.pone.0289707