Short hydrocarbon stapled ApoC2-mimetic peptides activate lipoprotein lipase and lower plasma triglycerides in mice

INTRODUCTION: Defects in lipolysis can lead to hypertriglyceridemia, which can trigger acute pancreatitis and is also associated with cardiovascular disease. Decreasing plasma triglycerides (TGs) by activating lipoprotein lipase (LPL) with ApoC2 mimetic peptides is a new treatment strategy for hyper...

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Detalles Bibliográficos
Autores principales: Sviridov, Denis, Dasseux, Amaury, Reimund, Mart, Pryor, Milton, Drake, Steven K., Jarin, Zack, Wolska, Anna, Pastor, Richard W., Remaley, Alan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403075/
https://www.ncbi.nlm.nih.gov/pubmed/37547254
http://dx.doi.org/10.3389/fcvm.2023.1223920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403075/
https://www.ncbi.nlm.nih.gov/pubmed/37547254
http://dx.doi.org/10.3389/fcvm.2023.1223920

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