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Evaluating the utility of brightfield image data for mechanism of action prediction

Fluorescence staining techniques, such as Cell Painting, together with fluorescence microscopy have proven invaluable for visualizing and quantifying the effects that drugs and other perturbations have on cultured cells. However, fluorescence microscopy is expensive, time-consuming, labor-intensive,...

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Detalles Bibliográficos
Autores principales: Harrison, Philip John, Gupta, Ankit, Rietdijk, Jonne, Wieslander, Håkan, Carreras-Puigvert, Jordi, Georgiev, Polina, Wählby, Carolina, Spjuth, Ola, Sintorn, Ida-Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403126/
https://www.ncbi.nlm.nih.gov/pubmed/37490493
http://dx.doi.org/10.1371/journal.pcbi.1011323