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Evaluating the utility of brightfield image data for mechanism of action prediction
Fluorescence staining techniques, such as Cell Painting, together with fluorescence microscopy have proven invaluable for visualizing and quantifying the effects that drugs and other perturbations have on cultured cells. However, fluorescence microscopy is expensive, time-consuming, labor-intensive,...
Autores principales: | Harrison, Philip John, Gupta, Ankit, Rietdijk, Jonne, Wieslander, Håkan, Carreras-Puigvert, Jordi, Georgiev, Polina, Wählby, Carolina, Spjuth, Ola, Sintorn, Ida-Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403126/ https://www.ncbi.nlm.nih.gov/pubmed/37490493 http://dx.doi.org/10.1371/journal.pcbi.1011323 |
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