Cargando…

In vivo Polycystin-1 interactome using a novel Pkd1 knock-in mouse model

PKD1 is the most commonly mutated gene causing autosomal dominant polycystic kidney disease (ADPKD). It encodes Polycystin-1 (PC1), a putative membrane protein that undergoes a set of incompletely characterized post-transcriptional cleavage steps and has been reported to localize in multiple subcell...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Cheng-Chao, Menezes, Luis F., Qiu, Jiahe, Pearson, Elisabeth, Zhou, Fang, Ishimoto, Yu, Anderson, D. Eric, Germino, Gregory G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403143/
https://www.ncbi.nlm.nih.gov/pubmed/37540694
http://dx.doi.org/10.1371/journal.pone.0289778