Cargando…
In vivo Polycystin-1 interactome using a novel Pkd1 knock-in mouse model
PKD1 is the most commonly mutated gene causing autosomal dominant polycystic kidney disease (ADPKD). It encodes Polycystin-1 (PC1), a putative membrane protein that undergoes a set of incompletely characterized post-transcriptional cleavage steps and has been reported to localize in multiple subcell...
Autores principales: | Lin, Cheng-Chao, Menezes, Luis F., Qiu, Jiahe, Pearson, Elisabeth, Zhou, Fang, Ishimoto, Yu, Anderson, D. Eric, Germino, Gregory G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403143/ https://www.ncbi.nlm.nih.gov/pubmed/37540694 http://dx.doi.org/10.1371/journal.pone.0289778 |
Ejemplares similares
-
Pkd1 and Pkd2 Are Required for Normal Placental Development
por: Garcia-Gonzalez, Miguel A., et al.
Publicado: (2010) -
Atypical calcium regulation of the PKD2-L1 polycystin ion channel
por: DeCaen, Paul G, et al.
Publicado: (2016) -
Naturally Occurring Mutations Alter the Stability of Polycystin-1 Polycystic Kidney Disease (PKD) Domains
por: Ma, Liang, et al.
Publicado: (2009) -
A mutation affecting polycystin-1 mediated heterotrimeric G-protein signaling causes PKD
por: Parnell, Stephen C, et al.
Publicado: (2018) -
PKD2/polycystin-2 inhibits LPS-induced acute lung injury in vitro and in vivo by activating autophagy
por: Pan, Fan, et al.
Publicado: (2023)