Clodronate is not protective in lethal viral encephalitis despite substantially reducing inflammatory monocyte infiltration in the CNS

Bone marrow (BM)-derived monocytes induce inflammation and tissue damage in a range of pathologies. In particular, in a mouse model of West Nile virus (WNV) encephalitis (WNE), nitric oxide-producing, Ly6C(hi) inflammatory monocytes from the BM are recruited to the central nervous system (CNS) and c...

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Detalles Bibliográficos
Autores principales: Spiteri, Alanna G., van Vreden, Caryn, Ashhurst, Thomas M., Niewold, Paula, King, Nicholas J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403146/
https://www.ncbi.nlm.nih.gov/pubmed/37545511
http://dx.doi.org/10.3389/fimmu.2023.1203561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403146/
https://www.ncbi.nlm.nih.gov/pubmed/37545511
http://dx.doi.org/10.3389/fimmu.2023.1203561

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