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Single-cell analysis of multiple invertible promoters reveals differential inversion rates as a strong determinant of bacterial population heterogeneity

Population heterogeneity can promote bacterial fitness in response to unpredictable environmental conditions. A major mechanism of phenotypic variability in the human gut symbiont Bacteroides spp. involves the inversion of promoters that drive the expression of capsular polysaccharides, which determ...

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Detalles Bibliográficos
Autores principales: Lan, Freeman, Saba, Jason, Qian, Yili, Ross, Tyler, Landick, Robert, Venturelli, Ophelia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403206/
https://www.ncbi.nlm.nih.gov/pubmed/37540747
http://dx.doi.org/10.1126/sciadv.adg5476