Calcineurin-independent NFATc1 signaling is essential for survival of Burkitt lymphoma cells

In Burkitt lymphoma (BL), a tumor of germinal center B cells, the pro-apoptotic properties of MYC are controlled by tonic B cell receptor (BCR) signals. Since BL cells do not exhibit constitutive NF-κB activity, we hypothesized that anti-apoptotic NFATc1 proteins provide a major transcriptional surv...

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Detalles Bibliográficos
Autores principales: Murti, Krisna, Fender, Hendrik, Glatzle, Carolin, Wismer, Rhoda, Sampere-Birlanga, Salvador, Wild, Vanessa, Muhammad, Khalid, Rosenwald, Andreas, Serfling, Edgar, Avots, Andris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403262/
https://www.ncbi.nlm.nih.gov/pubmed/37546418
http://dx.doi.org/10.3389/fonc.2023.1205788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403262/
https://www.ncbi.nlm.nih.gov/pubmed/37546418
http://dx.doi.org/10.3389/fonc.2023.1205788

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