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Calcineurin-independent NFATc1 signaling is essential for survival of Burkitt lymphoma cells
In Burkitt lymphoma (BL), a tumor of germinal center B cells, the pro-apoptotic properties of MYC are controlled by tonic B cell receptor (BCR) signals. Since BL cells do not exhibit constitutive NF-κB activity, we hypothesized that anti-apoptotic NFATc1 proteins provide a major transcriptional surv...
Autores principales: | Murti, Krisna, Fender, Hendrik, Glatzle, Carolin, Wismer, Rhoda, Sampere-Birlanga, Salvador, Wild, Vanessa, Muhammad, Khalid, Rosenwald, Andreas, Serfling, Edgar, Avots, Andris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403262/ https://www.ncbi.nlm.nih.gov/pubmed/37546418 http://dx.doi.org/10.3389/fonc.2023.1205788 |
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