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Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation

Microtubules play crucial roles in cellular architecture, intracellular transport, and mitosis. The availability of free tubulin subunits affects polymerization dynamics and microtubule function. When cells sense excess free tubulin, they trigger degradation of the encoding mRNAs, which requires rec...

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Detalles Bibliográficos
Autores principales: Höpfler, Markus, Absmeier, Eva, Peak-Chew, Sew-Yeu, Vartholomaiou, Evangelia, Passmore, Lori A., Gasic, Ivana, Hegde, Ramanujan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403363/
https://www.ncbi.nlm.nih.gov/pubmed/37295431
http://dx.doi.org/10.1016/j.molcel.2023.05.020