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Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation
Microtubules play crucial roles in cellular architecture, intracellular transport, and mitosis. The availability of free tubulin subunits affects polymerization dynamics and microtubule function. When cells sense excess free tubulin, they trigger degradation of the encoding mRNAs, which requires rec...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403363/ https://www.ncbi.nlm.nih.gov/pubmed/37295431 http://dx.doi.org/10.1016/j.molcel.2023.05.020 |