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Hypothermia increases cold-inducible protein expression and improves cerebellar dependent learning after hypoxia ischemia in the neonatal rat

BACKGROUND: Hypoxic ischemic encephalopathy remains a significant cause of developmental disability(1,2). The standard of care for term infants is hypothermia, which has multifactorial effects(3–5). Therapeutic hypothermia upregulates the cold-inducible protein RNA binding motif 3 (RBM3) that is hig...

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Detalles Bibliográficos
Autores principales: Perez-Pouchoulen, Miguel, Jaiyesimi, Ayodele, Bardhi, Keti, Waddell, Jaylyn, Banerjee, Aditi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403381/
https://www.ncbi.nlm.nih.gov/pubmed/36810641
http://dx.doi.org/10.1038/s41390-023-02535-z