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Synergistic effects of hormones on structural and functional maturation of cardiomyocytes and implications for heart regeneration
The limited endogenous regenerative capacity of the human heart renders cardiovascular diseases a major health threat, thus motivating intense research on in vitro heart cell generation and cell replacement therapies. However, so far, in vitro-generated cardiomyocytes share a rather fetal phenotype,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403476/ https://www.ncbi.nlm.nih.gov/pubmed/37541969 http://dx.doi.org/10.1007/s00018-023-04894-6 |