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Synergistic effects of hormones on structural and functional maturation of cardiomyocytes and implications for heart regeneration

The limited endogenous regenerative capacity of the human heart renders cardiovascular diseases a major health threat, thus motivating intense research on in vitro heart cell generation and cell replacement therapies. However, so far, in vitro-generated cardiomyocytes share a rather fetal phenotype,...

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Detalles Bibliográficos
Autores principales: Galow, Anne-Marie, Brenmoehl, Julia, Hoeflich, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403476/
https://www.ncbi.nlm.nih.gov/pubmed/37541969
http://dx.doi.org/10.1007/s00018-023-04894-6