Single-cell trajectory analysis reveals a CD9 positive state to contribute to exit from stem cell-like and embryonic diapause states and transit to drug-resistant states

Bromo- and extra-terminal domain (BET) inhibitors (BETi) have been shown to decrease tumor growth in preclinical models and clinical trials. However, toxicity and rapid emergence of resistance have limited their clinical implementation. To identify state changes underlying acquisition of resistance...

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Detalles Bibliográficos
Autores principales: Li, Xi, Poire, Alfonso, Jeong, Kang Jin, Zhang, Dong, Chen, Gang, Sun, Chaoyang, Mills, Gordon B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403509/
https://www.ncbi.nlm.nih.gov/pubmed/37542044
http://dx.doi.org/10.1038/s41420-023-01586-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403509/
https://www.ncbi.nlm.nih.gov/pubmed/37542044
http://dx.doi.org/10.1038/s41420-023-01586-9

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