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The AT-hook is an evolutionarily conserved auto-regulatory domain of SWI/SNF required for cell lineage priming
The SWI/SNF ATP-dependent chromatin remodeler is a master regulator of the epigenome, controlling pluripotency and differentiation. Towards the C-terminus of the catalytic subunit of SWI/SNF is a motif called the AT-hook that is evolutionary conserved. The AT-hook is present in many chromatin modifi...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403523/ https://www.ncbi.nlm.nih.gov/pubmed/37542049 http://dx.doi.org/10.1038/s41467-023-40386-8 |