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PersonALL: a genetic scoring guide for personalized risk assessment in pediatric B-cell precursor acute lymphoblastic leukemia

BACKGROUND: Recurrent genetic lesions provide basis for risk assessment in pediatric acute lymphoblastic leukemia (ALL). However, current prognostic classifiers rely on a limited number of predefined sets of alterations. METHODS: Disease-relevant copy number aberrations (CNAs) were screened genome-w...

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Detalles Bibliográficos
Autores principales: Bedics, Gábor, Egyed, Bálint, Kotmayer, Lili, Benard-Slagter, Anne, de Groot, Karel, Bekő, Anna, Hegyi, Lajos László, Bátai, Bence, Krizsán, Szilvia, Kriván, Gergely, Erdélyi, Dániel J., Müller, Judit, Haltrich, Irén, Kajtár, Béla, Pajor, László, Vojcek, Ágnes, Ottóffy, Gábor, Ujfalusi, Anikó, Szegedi, István, Tiszlavicz, Lilla Györgyi, Bartyik, Katalin, Csanádi, Krisztina, Péter, György, Simon, Réka, Hauser, Péter, Kelemen, Ágnes, Sebestyén, Endre, Jakab, Zsuzsanna, Matolcsy, András, Kiss, Csongor, Kovács, Gábor, Savola, Suvi, Bödör, Csaba, Alpár, Donát
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403542/
https://www.ncbi.nlm.nih.gov/pubmed/37340093
http://dx.doi.org/10.1038/s41416-023-02309-8