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Polymeric nature of tandemly repeated genes enhances assembly of constitutive heterochromatin in fission yeast

Motivated by our recent experiments that demonstrate that the tandemly repeated genes become heterochromatin, here we show a theory of heterochromatin assembly by taking into account the connectivity of these genes along the chromatin in the kinetic equations of small RNA production and histone meth...

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Detalles Bibliográficos
Autores principales: Yamamoto, Tetsuya, Asanuma, Takahiro, Murakami, Yota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403545/
https://www.ncbi.nlm.nih.gov/pubmed/37542144
http://dx.doi.org/10.1038/s42003-023-05154-w