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Structures and immune recognition of Env trimers from two Asia prevalent HIV-1 CRFs

Structure-guided immunofocusing HIV-1 vaccine design entails a comprehensive understanding of Envs from diverse HIV-1 subtypes, including circulating recombinant forms (CRFs). Here, we present the cryo-EM structures of Envs from two Asia prevalent CRFs (CRF01_AE and CRF07_BC) at 3.0 and 3.5 Å. We co...

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Detalles Bibliográficos
Autores principales: Niu, Jun, Wang, Qi, Zhao, Wenwen, Meng, Bing, Xu, Youwei, Zhang, Xianfang, Feng, Yi, Qi, Qilian, Hao, Yanling, Zhang, Xuan, Liu, Ying, Xiang, Jiangchao, Shao, Yiming, Yang, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403546/
https://www.ncbi.nlm.nih.gov/pubmed/37542068
http://dx.doi.org/10.1038/s41467-023-40321-x