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A human antibody epitope map of the malaria vaccine antigen Pfs25

Pfs25 is a leading antigen for a malaria transmission-blocking vaccine and shows moderate transmission-blocking activity and induction of rapidly decreasing antibody titers in clinical trials. A comprehensive definition of all transmission-reducing epitopes of Pfs25 will inform structure-guided desi...

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Detalles Bibliográficos
Autores principales: Shukla, Niharika, Tang, Wai Kwan, Coelho, Camila H., Long, Carole A., Healy, Sara A., Sagara, Issaka, Miura, Kazutoyo, Duffy, Patrick E., Tolia, Niraj H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403551/
https://www.ncbi.nlm.nih.gov/pubmed/37542029
http://dx.doi.org/10.1038/s41541-023-00712-z