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Copper(I)-catalyzed asymmetric 1,3-dipolar cycloaddition of 1,3-enynes and azomethine ylides

Herein, we report a copper(I)-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides and 1,3-enynes, which provides a series of chiral poly-substituted pyrrolidines in high regio-, diastereo-, and enantioselectivities. Both 4-aryl-1,3-enynes and 4-silyl-1,3-enynes serve as suitable dipo...

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Detalles Bibliográficos
Autores principales: Wang, Bo-Ran, Li, Yan-Bo, Zhang, Qi, Gao, Dingding, Tian, Ping, Li, Qinghua, Yin, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403559/
https://www.ncbi.nlm.nih.gov/pubmed/37542041
http://dx.doi.org/10.1038/s41467-023-40409-4