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Ribo-On and Ribo-Off tools using a self-cleaving ribozyme allow manipulation of endogenous gene expression in C. elegans

Investigating gene function relies on the efficient manipulation of endogenous gene expression. Currently, a limited number of tools are available to robustly manipulate endogenous gene expression between “on” and “off” states. In this study, we insert a 63 bp coding sequence of T3H38 ribozyme into...

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Detalles Bibliográficos
Autores principales: Fang, Jie, Wang, Jie, Wang, Yuzhi, Liu, Xiaofan, Chen, Baohui, Zou, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403566/
https://www.ncbi.nlm.nih.gov/pubmed/37542105
http://dx.doi.org/10.1038/s42003-023-05184-4