Arginine regulates HSPA5/BiP translation through ribosome pausing in triple-negative breast cancer cells

BACKGROUND: Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with a high mortality rate due to a lack of therapeutic targets. Many TNBC cells are reliant on extracellular arginine for survival and express high levels of binding immunoglobin protein (BiP), a marker of me...

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Detalles Bibliográficos
Autores principales: Vidal, Christina M., Ouyang, Ching, Qi, Yue, Mendez-Dorantes, Carlos, Coblentz, Alaysia, Alva-Ornelas, Jackelyn A., Stark, Jeremy M., Seewaldt, Victoria L., Ann, David K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403569/
https://www.ncbi.nlm.nih.gov/pubmed/37386138
http://dx.doi.org/10.1038/s41416-023-02322-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403569/
https://www.ncbi.nlm.nih.gov/pubmed/37386138
http://dx.doi.org/10.1038/s41416-023-02322-x

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