Chromatin accessibility uncovers KRAS-driven FOSL2 promoting pancreatic ductal adenocarcinoma progression through up-regulation of CCL28

BACKGROUND: The epigenetic mechanisms involved in the progression of pancreatic ductal adenocarcinoma (PDAC) remain largely unexplored. This study aimed to identify key transcription factors (TFs) through multiomics sequencing to investigate the molecular mechanisms of TFs that play critical roles i...

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Detalles Bibliográficos
Autores principales: Zhang, Shujun, Li, Peilong, Li, Juan, Gao, Jie, Qi, Qiuchen, Dong, Guoying, Liu, Xiaoyan, Jiao, Qinlian, Wang, Yunshan, Du, Lutao, Zhan, Hanxiang, Xu, Shuo, Wang, Chuanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403592/
https://www.ncbi.nlm.nih.gov/pubmed/37380804
http://dx.doi.org/10.1038/s41416-023-02313-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403592/
https://www.ncbi.nlm.nih.gov/pubmed/37380804
http://dx.doi.org/10.1038/s41416-023-02313-y

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