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Chromatin accessibility uncovers KRAS-driven FOSL2 promoting pancreatic ductal adenocarcinoma progression through up-regulation of CCL28
BACKGROUND: The epigenetic mechanisms involved in the progression of pancreatic ductal adenocarcinoma (PDAC) remain largely unexplored. This study aimed to identify key transcription factors (TFs) through multiomics sequencing to investigate the molecular mechanisms of TFs that play critical roles i...
Autores principales: | Zhang, Shujun, Li, Peilong, Li, Juan, Gao, Jie, Qi, Qiuchen, Dong, Guoying, Liu, Xiaoyan, Jiao, Qinlian, Wang, Yunshan, Du, Lutao, Zhan, Hanxiang, Xu, Shuo, Wang, Chuanxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403592/ https://www.ncbi.nlm.nih.gov/pubmed/37380804 http://dx.doi.org/10.1038/s41416-023-02313-y |
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