Loss of Pkd1 limits susceptibility to colitis and colorectal cancer

Colorectal cancer (CRC) is one of the most common cancers, with an annual incidence of ~135,000 in the US, associated with ~50,000 deaths. Autosomal dominant polycystic kidney disease (ADPKD), associated with mutations disabling the PKD1 gene, affects as many as 1 in 1000. Intriguingly, some studies...

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Detalles Bibliográficos
Autores principales: Nikonova, Anna S., Deneka, Alexander Y., Silva, Flaviane N., Pirestani, Shabnam, Tricarico, Rossella, Kiseleva, Anna A., Zhou, Yan, Nicolas, Emmanuelle, Flieder, Douglas B., Grivennikov, Sergei I., Golemis, Erica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403611/
https://www.ncbi.nlm.nih.gov/pubmed/37542051
http://dx.doi.org/10.1038/s41389-023-00486-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403611/
https://www.ncbi.nlm.nih.gov/pubmed/37542051
http://dx.doi.org/10.1038/s41389-023-00486-y

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