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Treatment of CHO cells with Taxol and reversine improves micronucleation and microcell-mediated chromosome transfer efficiency

Microcell-mediated chromosome transfer is an attractive technique for transferring chromosomes from donor cells to recipient cells and has enabled the generation of cell lines and humanized animal models that contain megabase-sized gene(s). However, improvements in chromosomal transfer efficiency ar...

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Detalles Bibliográficos
Autores principales: Uno, Narumi, Satofuka, Hiroyuki, Miyamoto, Hitomaru, Honma, Kazuhisa, Suzuki, Teruhiko, Yamazaki, Kyotaro, Ito, Ryota, Moriwaki, Takashi, Hamamichi, Shusei, Tomizuka, Kazuma, Oshimura, Mitsuo, Kazuki, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403731/
https://www.ncbi.nlm.nih.gov/pubmed/37547291
http://dx.doi.org/10.1016/j.omtn.2023.07.002