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Therapeutic inhibition of miR-155 attenuates liver fibrosis via STAT3 signaling

Most chronic liver diseases progress to liver fibrosis, which, when left untreated, can lead to cirrhosis and hepatocellular carcinoma. MicroRNA (miRNA)-targeted therapeutics have become attractive approaches to treat diseases. In this study, we investigated the therapeutic effect of miR-155 inhibit...

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Detalles Bibliográficos
Autores principales: Bala, Shashi, Zhuang, Yuan, Nagesh, Prashanth Thevkar, Catalano, Donna, Zivny, Adam, Wang, Yanbo, Xie, Jun, Gao, Guangping, Szabo, Gyongyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403732/
https://www.ncbi.nlm.nih.gov/pubmed/37547286
http://dx.doi.org/10.1016/j.omtn.2023.07.012