PAI1 inhibits the pathogenesis of primary focal hyperhidrosis by targeting CHRNA1

BACKGROUND: Primary focal hyperhidrosis (PFH) may be attributed to the up-regulation of the cholinergic receptor nicotinic alpha 1 subunit (CHRNA1) in eccrine glands. Plasminogen activator inhibitor-1 (PAI1, encoded by SERPINE1) is reported to inhibit the expression of CHRNA1, while the role of PAI1...

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Detalles Bibliográficos
Autores principales: Chen, Jian-Feng, Lin, Min, Li, Xu, Lin, Jian-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403875/
https://www.ncbi.nlm.nih.gov/pubmed/37542348
http://dx.doi.org/10.1186/s13023-023-02808-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403875/
https://www.ncbi.nlm.nih.gov/pubmed/37542348
http://dx.doi.org/10.1186/s13023-023-02808-0

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