FACT regulates pluripotency through proximal and distal regulation of gene expression in murine embryonic stem cells

BACKGROUND: The FACT complex is a conserved histone chaperone with critical roles in transcription and histone deposition. FACT is essential in pluripotent and cancer cells, but otherwise dispensable for most mammalian cell types. FACT deletion or inhibition can block induction of pluripotent stem c...

Descripción completa

Detalles Bibliográficos
Autores principales: Klein, David C., Lardo, Santana M., McCannell, Kurtis N., Hainer, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403911/
https://www.ncbi.nlm.nih.gov/pubmed/37542287
http://dx.doi.org/10.1186/s12915-023-01669-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403911/
https://www.ncbi.nlm.nih.gov/pubmed/37542287
http://dx.doi.org/10.1186/s12915-023-01669-0

Ejemplares similares