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How do prolonged anchorage-free lifetimes strengthen non-small-cell lung cancer cells to evade anoikis? – A link with altered cellular metabolomics

BACKGROUND: Malignant cells adopt anoikis resistance to survive anchorage-free stresses and initiate cancer metastasis. It is still unknown how varying periods of anchorage loss contribute to anoikis resistance, cell migration, and metabolic reprogramming of cancerous cells. RESULTS: Our study demon...

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Detalles Bibliográficos
Autores principales: Sungthong, Rungroch, Khine, Hnin Ei Ei, Sumkhemthong, Somruethai, Chanvorachote, Pithi, Tansawat, Rossarin, Chaotham, Chatchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403914/
https://www.ncbi.nlm.nih.gov/pubmed/37542350
http://dx.doi.org/10.1186/s40659-023-00456-z