Decreased TMIGD1 aggravates colitis and intestinal barrier dysfunction via the BANF1-NF-κB pathway in Crohn’s disease

BACKGROUND: Disrupted intestinal epithelial barrier is one of the major causes of Crohn’s disease (CD). Novel molecular targets for intestinal epithelial barrier are essential to treatment of CD. Transmembrane and immunoglobulin domain-containing protein 1 (TMIGD1) is an adhesion molecule that regul...

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Detalles Bibliográficos
Autores principales: Zhou, Longyuan, Zhu, Liguo, Wu, Xiaomin, Hu, Shixian, Zhang, Shenghong, Ning, Min, Yu, Jun, Chen, Minhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403950/
https://www.ncbi.nlm.nih.gov/pubmed/37542259
http://dx.doi.org/10.1186/s12916-023-02989-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403950/
https://www.ncbi.nlm.nih.gov/pubmed/37542259
http://dx.doi.org/10.1186/s12916-023-02989-2

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