Cargando…

Decreased TMIGD1 aggravates colitis and intestinal barrier dysfunction via the BANF1-NF-κB pathway in Crohn’s disease

BACKGROUND: Disrupted intestinal epithelial barrier is one of the major causes of Crohn’s disease (CD). Novel molecular targets for intestinal epithelial barrier are essential to treatment of CD. Transmembrane and immunoglobulin domain-containing protein 1 (TMIGD1) is an adhesion molecule that regul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Longyuan, Zhu, Liguo, Wu, Xiaomin, Hu, Shixian, Zhang, Shenghong, Ning, Min, Yu, Jun, Chen, Minhu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403950/ https://www.ncbi.nlm.nih.gov/pubmed/37542259 http://dx.doi.org/10.1186/s12916-023-02989-2

Ejemplares similares

Genome-wide RNAi screening identifies TMIGD3 isoform1 as a suppressor of NF-κB and osteosarcoma progression
por: Iyer, Swathi V., et al.
Publicado: (2016)

BANFE-3 : Batería Neuropsicológica de Funciones Ejecutivas y Lóbulos Frontales : Manual /
por: Flores Lázaro, Julio César
Publicado: (2020)

TMIGD1: Emerging functions of a tumor supressor and adhesion receptor
por: Thüring, Eva-Maria, et al.
Publicado: (2023)

Expression and Prognostic Significance of BANF1 in Triple-Negative Breast Cancer
por: Zhang, Genhao
Publicado: (2020)

The Impact of Rare Human Variants on Barrier-To-Auto-Integration Factor 1 (Banf1) Structure and Function
por: Rose, Maddison, et al.
Publicado: (2021)

Membrane recruitment of the polarity protein Scribble by the cell adhesion receptor TMIGD1
por: Thüring, Eva-Maria, et al.
Publicado: (2023)

BANF1 Is Downregulated by IRF1-Regulated MicroRNA-203 in Cervical Cancer
por: Mao, Langyong, et al.
Publicado: (2015)

TMIGD2 as a potential therapeutic target in glioma patients
por: Boulhen, Chaimae, et al.
Publicado: (2023)

Correction: BANF1 Is Downregulated by IRF1-Regulated MicroRNA-203 in Cervical Cancer
Publicado: (2015)

The cell adhesion molecule TMIGD1 binds to moesin and regulates tubulin acetylation and cell migration
por: Rahimi, Nader, et al.
Publicado: (2021)

Ulcerative colitis increases risk of hypertension in a UK biobank cohort study
por: He, Jinshen, et al.
Publicado: (2022)

TMIGD1 Inhibited Abdominal Adhesion Formation by Alleviating Oxidative Stress in the Mitochondria of Peritoneal Mesothelial Cells
por: Wu, Yunhua, et al.
Publicado: (2021)

Latexin deficiency in mice up-regulates inflammation and aggravates colitis through HECTD1/Rps3/NF-κB pathway
por: Li, Yaping, et al.
Publicado: (2020)

Downregulation of VRK1 reduces the expression of BANF1 and suppresses the proliferative and migratory activity of esophageal cancer cells
por: Ren, Zhenzhen, et al.
Publicado: (2020)

Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage
por: Bolderson, Emma, et al.
Publicado: (2019)

Mechanisms of A-Type Lamin Targeting to Nuclear Ruptures Are Disrupted in LMNA- and BANF1-Associated Progerias
por: Sears, Rhiannon M., et al.
Publicado: (2022)

Gene Variant of Barrier to Autointegration Factor 2 (Banf2w) Is Concordant with Female Determination in Cichlids
por: Curzon, Arie Yehuda, et al.
Publicado: (2021)

Deficiency of Nuclear Receptor Nur77 Aggravates Mouse Experimental Colitis by Increased NFκB Activity in Macrophages
por: Hamers, Anouk A. J., et al.
Publicado: (2015)

Decreased miR-214–3p activates NF-κB pathway and aggravates osteoarthritis progression
por: Cao, Yumei, et al.
Publicado: (2021)

DNA Methylation of miR-122 Aggravates Oxidative Stress in Colitis Targeting SELENBP1 Partially by p65NF-κB Signaling
por: Bai, Jianan, et al.
Publicado: (2019)

Trajectory of fecal lactoferrin for predicting prognosis in ulcerative colitis
por: Chen, Rirong, et al.
Publicado: (2023)

TMIGD1 acts as a tumor suppressor through regulation of p21Cip1/p27Kip1 in renal cancer
por: Meyer, Rosana D., et al.
Publicado: (2017)

Barrier-to-Autointegration Factor 1 (BAF/BANF1) Promotes Association of the SETD1A Histone Methyltransferase with Herpes Simplex Virus Immediate-Early Gene Promoters
por: Oh, Hyung Suk, et al.
Publicado: (2015)

A new DNA marker of the TMIGD1 gene used to identify high fertilization rates in Tsaiya ducks (Anas platyrhynchos)
por: HUANG, Hsiu-Lin, et al.
Publicado: (2018)

The mitochondrial outer membrane protein SYNJ2BP interacts with the cell adhesion molecule TMIGD1 and can recruit it to mitochondria
por: Hartmann, Christian, et al.
Publicado: (2020)

Notch4 activation aggravates NF-κB-mediated inflammation in HIV-1-associated nephropathy
por: Puri, Rajni Vaid, et al.
Publicado: (2019)

Inhibition of tumor intrinsic BANF1 activates antitumor immune responses via cGAS-STING and enhances the efficacy of PD-1 blockade
por: Wang, Minglei, et al.
Publicado: (2023)

Acrylamide exposure aggravates the development of ulcerative colitis in mice through activation of NF-κB, inflammatory cytokines, iNOS, and oxidative stress
por: Amirshahrokhi, Keyvan
Publicado: (2021)

Hypermethylation of miR-145 promoter-mediated SOX9-CLDN8 pathway regulates intestinal mucosal barrier in Crohn's disease
por: Zhuang, Xiaojun, et al.
Publicado: (2022)

TRPA1 mediated aggravation of allergic contact dermatitis induced by DINP and regulated by NF-κB activation
por: Kang, Jun, et al.
Publicado: (2017)

PINCH1 knockout aggravates myocardial infarction in mice via mediating the NF-κB signaling pathway
por: Wang, Xuejun, et al.
Publicado: (2022)

Chemokine‐like factor 1 (CKLF1) aggravates neointimal hyperplasia through activating the NF‐κB /VCAM‐1 pathway
por: Liu, Xinnong, et al.
Publicado: (2020)

Barrier-to-autointegration-factor (Banf1) modulates DNA double-strand break repair pathway choice via regulation of DNA-dependent kinase (DNA-PK) activity
por: Burgess, Joshua T, et al.
Publicado: (2021)

Mucosal Barrier in Ulcerative Colitis and Crohn's Disease
por: Dorofeyev, A. E., et al.
Publicado: (2013)

Tozinameran: Aggravation of Crohn's disease: case report
Publicado: (2021)

Prognostic models for predicting postoperative recurrence in Crohn’s disease: a systematic review and critical appraisal
por: Chen, Rirong, et al.
Publicado: (2023)

A Novel Model Based on Serum Biomarkers to Predict Primary Non-Response to Infliximab in Crohn’s Disease
por: Li, Li, et al.
Publicado: (2021)

Development and validation of a non-invasive biomarker-based model to identify endoscopic recurrences of Crohn’s disease
por: Zhou, Gaoshi, et al.
Publicado: (2022)

Fecal lactoferrin early predicts long‐term outcomes in ulcerative colitis: A post‐hoc analysis of the UNIFI and PURSUIT trials
por: Chen, Rirong, et al.
Publicado: (2023)

Protocadherin 20 maintains intestinal barrier function to protect against Crohn’s disease by targeting ATF6
por: Huang, Shanshan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_0h2o2utsono2hqh8tsnpe4m1ep