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Mixed IgG Fc immune complexes exhibit blended binding profiles and refine FcR affinity estimates
Immunoglobulin G (IgG) antibodies coordinate immune effector responses by interacting with effector cells via fragment crystallizable γ (Fcγ) receptors. The IgG Fc domain directs effector responses through subclass and glycosylation variation. Although each Fc variant has been extensively characteri...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404157/ https://www.ncbi.nlm.nih.gov/pubmed/37421619 http://dx.doi.org/10.1016/j.celrep.2023.112734 |