Genotoxicity assessment: opportunities, challenges and perspectives for quantitative evaluations of dose–response data

Genotoxicity data are mainly interpreted in a qualitative way, which typically results in a binary classification of chemical entities. For more than a decade, there has been a discussion about the need for a paradigm shift in this regard. Here, we review current opportunities, challenges and perspe...

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Detalles Bibliográficos
Autores principales: Menz, Jakob, Götz, Mario E., Gündel, Ulrike, Gürtler, Rainer, Herrmann, Kristin, Hessel-Pras, Stefanie, Kneuer, Carsten, Kolrep, Franziska, Nitzsche, Dana, Pabel, Ulrike, Sachse, Benjamin, Schmeisser, Sebastian, Schumacher, David M., Schwerdtle, Tanja, Tralau, Tewes, Zellmer, Sebastian, Schäfer, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404208/
https://www.ncbi.nlm.nih.gov/pubmed/37402810
http://dx.doi.org/10.1007/s00204-023-03553-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404208/
https://www.ncbi.nlm.nih.gov/pubmed/37402810
http://dx.doi.org/10.1007/s00204-023-03553-w

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