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Transposable elements potentiate radiotherapy-induced cellular immune reactions via RIG-I-mediated virus-sensing pathways

Radiotherapy (RT) plus immunotherapy is a promising modality; however, the therapeutic effects are insufficient, and the molecular mechanism requires clarification to further develop combination therapies. Here, we found that the RNA virus sensor pathway dominantly regulates the cellular immune resp...

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Detalles Bibliográficos
Autores principales: Du, Junyan, Kageyama, Shun-Ichiro, Yamashita, Riu, Tanaka, Kosuke, Okumura, Masayuki, Motegi, Atsushi, Hojo, Hidehiro, Nakamura, Masaki, Hirata, Hidenari, Sunakawa, Hironori, Kotani, Daisuke, Yano, Tomonori, Kojima, Takashi, Hamaya, Yamato, Kojima, Motohiro, Nakamura, Yuka, Suzuki, Ayako, Suzuki, Yutaka, Tsuchihara, Katsuya, Akimoto, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404237/
https://www.ncbi.nlm.nih.gov/pubmed/37543704
http://dx.doi.org/10.1038/s42003-023-05080-x