Cargando…

Transposable elements potentiate radiotherapy-induced cellular immune reactions via RIG-I-mediated virus-sensing pathways

Radiotherapy (RT) plus immunotherapy is a promising modality; however, the therapeutic effects are insufficient, and the molecular mechanism requires clarification to further develop combination therapies. Here, we found that the RNA virus sensor pathway dominantly regulates the cellular immune resp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Du, Junyan, Kageyama, Shun-Ichiro, Yamashita, Riu, Tanaka, Kosuke, Okumura, Masayuki, Motegi, Atsushi, Hojo, Hidehiro, Nakamura, Masaki, Hirata, Hidenari, Sunakawa, Hironori, Kotani, Daisuke, Yano, Tomonori, Kojima, Takashi, Hamaya, Yamato, Kojima, Motohiro, Nakamura, Yuka, Suzuki, Ayako, Suzuki, Yutaka, Tsuchihara, Katsuya, Akimoto, Tetsuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404237/ https://www.ncbi.nlm.nih.gov/pubmed/37543704 http://dx.doi.org/10.1038/s42003-023-05080-x

Ejemplares similares

Impacts of the STING‐IFNAR1‐STAT1‐IRF1 pathway on the cellular immune reaction induced by fractionated irradiation
por: Du, Junyan, et al.
Publicado: (2022)

PARP inhibitor olaparib sensitizes esophageal carcinoma cells to fractionated proton irradiation
por: Kageyama, Shun-ichiro, et al.
Publicado: (2020)

Comprehensive screening for drugs that modify radiation-induced immune responses
por: Okumura, Masayuki, et al.
Publicado: (2022)

Tumor response and survival outcomes of salvage concurrent chemoradiotherapy with three-dimensional conformal radiotherapy and 5-fluorouracil/platinum-based chemotherapy for postoperative locoregional recurrence of esophageal squamous cell carcinoma
por: Ito, Renma, et al.
Publicado: (2022)

Classification and characterization of alternative promoters in 26 lung adenocarcinoma cell lines
por: Hamaya, Yamato, et al.
Publicado: (2022)

Radiotherapy increases plasma levels of tumoral cell-free DNA in non-small cell lung cancer patients
por: Kageyama, Shun-ichiro, et al.
Publicado: (2018)

Correction: Radiotherapy increases plasma levels of tumoral cell-free DNA in non-small cell lung cancer patients
por: Kageyama, Shun-Ichiro, et al.
Publicado: (2018)

Difference in the relative biological effectiveness and DNA damage repair processes in response to proton beam therapy according to the positions of the spread out Bragg peak
por: Hojo, Hidehiro, et al.
Publicado: (2017)

Comparison of a Hybrid IMRT/VMAT technique with non-coplanar VMAT and non-coplanar IMRT for unresectable olfactory neuroblastoma using the RayStation treatment planning system—EUD, NTCP and planning study
por: Raturi, Vijay P, et al.
Publicado: (2021)

Dosimetric comparison between proton beam therapy and photon radiation therapy for locally advanced esophageal squamous cell carcinoma
por: Hirano, Yasuhiro, et al.
Publicado: (2018)

Palliative Radiation Therapy for Macroscopic Hematuria Caused by Urothelial Cancer
por: Zhang, Haiqin, et al.
Publicado: (2020)

Late radiological changes after passive scattering proton beam therapy for Stage I lung cancer
por: Nakamura, Naoki, et al.
Publicado: (2018)

Clinicopathological features and endoscopic characteristics of inverted sessile serrated adenomas/polyps
por: Takashima, Kenji, et al.
Publicado: (2019)

Radiobiological model-based approach to determine the potential of dose-escalated robust intensity-modulated proton radiotherapy in reducing gastrointestinal toxicity in the treatment of locally advanced unresectable pancreatic cancer of the head
por: Raturi, Vijay P., et al.
Publicado: (2020)

Post-mastectomy radiation therapy without usage of a bolus may be a reasonable option
por: Nakamura, Naoki, et al.
Publicado: (2017)

Impact of prophylactic cranial irradiation on pattern of brain metastases as a first recurrence site for limited-disease small-cell lung cancer
por: Nakamura, Masaki, et al.
Publicado: (2018)

Dose–Volume and Radiobiological Model-Based Comparative Evaluation of the Gastrointestinal Toxicity Risk of Photon and Proton Irradiation Plans in Localized Pancreatic Cancer Without Distant Metastasis
por: Raturi, Vijay P., et al.
Publicado: (2020)

Fecal microbiota in patients with a stoma decreases anaerobic bacteria and alters taxonomic and functional diversities
por: Sakai, Shunsuke A., et al.
Publicado: (2022)

Human transposable elements in Repbase: genomic footprints from fish to humans
por: Kojima, Kenji K.
Publicado: (2018)

Families of transposable elements, population structure and the origin of species
por: Jurka, Jerzy, et al.
Publicado: (2011)

Endoscopic resection combined with the Cryoballoon focal ablation system in the porcine normal esophagus: a preclinical study
por: Sunakawa, Hironori, et al.
Publicado: (2021)

DBTSS as an integrative platform for transcriptome, epigenome and genome sequence variation data
por: Suzuki, Ayako, et al.
Publicado: (2014)

TENERGY: multicenter phase II study of Atezolizumab monotherapy following definitive Chemoradiotherapy with 5-FU plus Cisplatin in patients with unresectable locally advanced esophageal squamous cell carcinoma
por: Bando, Hideaki, et al.
Publicado: (2020)

Diagnostic ability of Japan Narrow-Band Imaging Expert Team classification for colorectal lesions by magnifying endoscopy with blue laser imaging versus narrow-band imaging
por: Ito, Renma, et al.
Publicado: (2021)

Neoadjuvant S-1 with concurrent radiotherapy followed by surgery for borderline resectable pancreatic cancer: study protocol for an open-label, multicentre, prospective phase II trial (JASPAC05)
por: Takahashi, Shinichiro, et al.
Publicado: (2017)

Immunohistochemistry and oxygen saturation endoscopic imaging reveal hypoxia in submucosal invasive esophageal squamous cell carcinoma
por: Minakata, Nobuhisa, et al.
Publicado: (2023)

Efficacy and safety of repeated endoscopic radial incision and cutting procedure for benign esophageal stricture
por: Kano, Yuki, et al.
Publicado: (2023)

The “histological replacement growth pattern” represents aggressive invasive behavior in liver metastasis from pancreatic cancer
por: Watanabe, Kazuo, et al.
Publicado: (2020)

Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast
por: Nagasawa, Satoi, et al.
Publicado: (2021)

Rig it right!: Maya animation rigging concepts
por: O'Hailey, Tina
Publicado: (2013)

Usefulness of hybrid deformable image registration algorithms in prostate radiation therapy
por: Motegi, Kana, et al.
Publicado: (2018)

Improved efficacy of taxanes and ramucirumab combination chemotherapy after exposure to anti-PD-1 therapy in advanced gastric cancer
por: Sasaki, Akinori, et al.
Publicado: (2020)

Safety of endoscopic procedures with monopolar versus bipolar instruments in an ex vivo porcine model
por: Shinmura, Kensuke, et al.
Publicado: (2020)

Hydroxyapatite Formation on Self-Assembling Peptides with Differing Secondary Structures and Their Selective Adsorption for Proteins
por: Kojima, Suzuka, et al.
Publicado: (2019)

Single-cell analysis of lung adenocarcinoma cell lines reveals diverse expression patterns of individual cells invoked by a molecular target drug treatment
por: Suzuki, Ayako, et al.
Publicado: (2015)

Efficacy of a novel self-assembling peptide gel for hemostasis in refractory neoplastic bleeding
por: Kano, Yuki, et al.
Publicado: (2023)

Hypermutation and unique mutational signatures of occupational cholangiocarcinoma in printing workers exposed to haloalkanes
por: Mimaki, Sachiyo, et al.
Publicado: (2016)

Aberrant transcriptional regulations in cancers: genome, transcriptome and epigenome analysis of lung adenocarcinoma cell lines
por: Suzuki, Ayako, et al.
Publicado: (2014)

Identification of potential regulatory mutations using multi-omics analysis and haplotyping of lung adenocarcinoma cell lines
por: Sereewattanawoot, Sarun, et al.
Publicado: (2018)

The Influence of Feeding Pattern on Changes in Plasma Ghrelin in the Holstein Cow
por: MIURA, Hiroshi, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_eg3hjbia2ndiqo042cvr6gcd1g