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PP2A-B55alpha controls keratinocyte adhesion through dephosphorylation of the Desmoplakin C-terminus

Critical for the maintenance of epidermal integrity and function are attachments between intermediate filaments (IF) and intercellular junctions called desmosomes. The desmosomal cytoplasmic plaque protein desmoplakin (DP) is essential for anchoring IF to the junction. DP-IF interactions are regulat...

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Detalles Bibliográficos
Autores principales: Perl, Abbey L., Koetsier, Jennifer L., Green, Kathleen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404246/
https://www.ncbi.nlm.nih.gov/pubmed/37543698
http://dx.doi.org/10.1038/s41598-023-37874-8