Molecular basis of Mg(2+) permeation through the human mitochondrial Mrs2 channel

Mitochondrial RNA splicing 2 (Mrs2), a eukaryotic CorA ortholog, enables Mg(2+) to permeate the inner mitochondrial membrane and plays an important role in mitochondrial metabolic function. However, the mechanism by which Mrs2 permeates Mg(2+) remains unclear. Here, we report four cryo-electron micr...

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Detalles Bibliográficos
Autores principales: Li, Ming, Li, Yang, Lu, Yue, Li, Jianhui, Lu, Xuhang, Ren, Yue, Wen, Tianlei, Wang, Yaojie, Chang, Shenghai, Zhang, Xing, Yang, Xue, Shen, Yuequan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404273/
https://www.ncbi.nlm.nih.gov/pubmed/37543649
http://dx.doi.org/10.1038/s41467-023-40516-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404273/
https://www.ncbi.nlm.nih.gov/pubmed/37543649
http://dx.doi.org/10.1038/s41467-023-40516-2

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