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Molecular basis of Mg(2+) permeation through the human mitochondrial Mrs2 channel
Mitochondrial RNA splicing 2 (Mrs2), a eukaryotic CorA ortholog, enables Mg(2+) to permeate the inner mitochondrial membrane and plays an important role in mitochondrial metabolic function. However, the mechanism by which Mrs2 permeates Mg(2+) remains unclear. Here, we report four cryo-electron micr...
Autores principales: | Li, Ming, Li, Yang, Lu, Yue, Li, Jianhui, Lu, Xuhang, Ren, Yue, Wen, Tianlei, Wang, Yaojie, Chang, Shenghai, Zhang, Xing, Yang, Xue, Shen, Yuequan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404273/ https://www.ncbi.nlm.nih.gov/pubmed/37543649 http://dx.doi.org/10.1038/s41467-023-40516-2 |
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