Deficiency of BAP1 inhibits neuroblastoma tumorigenesis through destabilization of MYCN

The transcription factor MYCN is frequently amplified and overexpressed in a variety of cancers including high-risk neuroblastoma (NB) and promotes tumor cell proliferation, survival, and migration. Therefore, MYCN is being pursued as an attractive therapeutic target for selective inhibition of its...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoling, Cong, Xianling, Jin, Xiangting, Liu, Yu’e, Zhang, Tong, Fan, Xinyuan, Shi, Xiyao, Zhang, Xiaoying, Wang, Xue, Yang, Yong-Guang, Dai, Xiangpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404282/
https://www.ncbi.nlm.nih.gov/pubmed/37543638
http://dx.doi.org/10.1038/s41419-023-06030-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404282/
https://www.ncbi.nlm.nih.gov/pubmed/37543638
http://dx.doi.org/10.1038/s41419-023-06030-5

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