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Deficiency of BAP1 inhibits neuroblastoma tumorigenesis through destabilization of MYCN
The transcription factor MYCN is frequently amplified and overexpressed in a variety of cancers including high-risk neuroblastoma (NB) and promotes tumor cell proliferation, survival, and migration. Therefore, MYCN is being pursued as an attractive therapeutic target for selective inhibition of its...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404282/ https://www.ncbi.nlm.nih.gov/pubmed/37543638 http://dx.doi.org/10.1038/s41419-023-06030-5 |