Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation

The inability of adult human cardiomyocytes to proliferate is an obstacle to efficient cardiac regeneration after injury. Understanding the mechanisms that drive postnatal cardiomyocytes to switch to a non-regenerative state is therefore of great significance. Here we show that Arid1a, a subunit of...

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Detalles Bibliográficos
Autores principales: Boogerd, Cornelis J., Perini, Ilaria, Kyriakopoulou, Eirini, Han, Su Ji, La, Phit, van der Swaan, Britt, Berkhout, Jari B., Versteeg, Danielle, Monshouwer-Kloots, Jantine, van Rooij, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404286/
https://www.ncbi.nlm.nih.gov/pubmed/37543677
http://dx.doi.org/10.1038/s41467-023-40203-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404286/
https://www.ncbi.nlm.nih.gov/pubmed/37543677
http://dx.doi.org/10.1038/s41467-023-40203-2

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