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Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation
The inability of adult human cardiomyocytes to proliferate is an obstacle to efficient cardiac regeneration after injury. Understanding the mechanisms that drive postnatal cardiomyocytes to switch to a non-regenerative state is therefore of great significance. Here we show that Arid1a, a subunit of...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404286/ https://www.ncbi.nlm.nih.gov/pubmed/37543677 http://dx.doi.org/10.1038/s41467-023-40203-2 |