Muc2-dependent microbial colonization of the jejunal mucus layer is diet sensitive and confers local resistance to enteric pathogen infection

Intestinal mucus barriers normally prevent microbial infections but are sensitive to diet-dependent changes in the luminal environment. Here we demonstrate that mice fed a Western-style diet (WSD) suffer regiospecific failure of the mucus barrier in the small intestinal jejunum caused by diet-induce...

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Detalles Bibliográficos
Autores principales: Birchenough, George M.H., Schroeder, Bjoern O., Sharba, Sinan, Arike, Liisa, Recktenwald, Christian V., Puértolas-Balint, Fabiola, Subramani, Mahadevan V., Hansson, Karl T., Yilmaz, Bahtiyar, Lindén, Sara K., Bäckhed, Fredrik, Hansson, Gunnar C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404306/
https://www.ncbi.nlm.nih.gov/pubmed/36753416
http://dx.doi.org/10.1016/j.celrep.2023.112084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404306/
https://www.ncbi.nlm.nih.gov/pubmed/36753416
http://dx.doi.org/10.1016/j.celrep.2023.112084

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