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Beneficial Effects of a Curcumin Derivative and Transforming Growth Factor-β Receptor I Inhibitor Combination on Nonalcoholic Steatohepatitis

BACKGROUND: Curcumin 2005-8 (Cur5-8), a derivative of curcumin, improves fatty liver disease via AMP-activated protein kinase activation and autophagy regulation. EW-7197 (vactosertib) is a small molecule inhibitor of transforming growth factor β (TGF-β) receptor I and may scavenge reactive oxygen s...

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Detalles Bibliográficos
Autores principales: Ha, Kyung Bong, Lee, Eun Soo, Park, Na Won, Jo, Su Ho, Shim, Soyeon, Kim, Dae-Kee, Ahn, Chan Mug, Chung, Choon Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Diabetes Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404525/
https://www.ncbi.nlm.nih.gov/pubmed/37096379
http://dx.doi.org/10.4093/dmj.2022.0110